Careers

Careers at Loxo


About Loxo Oncology: Loxo Oncology is dedicated to developing highly selective medicines for patients with genetically defined cancers. We base our approach on two scientific trends: the increasing use of genetic testing in cancer clinical medicine and improving chemistry approaches to building highly selective inhibitors against single targets in the cancer cell.  

Some people develop cancers that are caused by a single inappropriate DNA change, known as “oncogenic drivers.” When a genetic test identifies a patient with an oncogenic driver, there should be a personalized medicine to address this error in the DNA that is leading to the cancer. At Loxo Oncology, we are developing a pipeline of highly selective drugs that inhibit oncogenic drivers in cancer.

/Loxô/ is a term from Greek mythology that refers to the trajectory of an arrow, a fitting metaphor for our approach to developing precise, targeted therapies against genetically defined cancers.


Location:

Stamford, CT

Reports To:

AP Analyst

Position Summary

Based in Stamford, CT, the Accounts Payable (AP) Coordinator will ensure that invoices, purchase orders, payments, and other company expenses are processed accurately and timely, and that excellent relationships are maintained with our vendors and functional internal leads. This individual must possess great attention to detail, meticulous organization skills, and a strong desire and ability to work within a dynamic, fast-paced environment with the expectations of the role consistently growing and expanding. The role will be responsible for but not limited to the items listed below.

Roles and Responsibilities of the Position*

  • Responsible for reviewing and transferring invoices from invoice mailbox to cloud storage.
  • Record invoices and credits into AP system module.
  • Compares incoming invoicing against contracts and purchase orders to ensure accuracy.
  • Respond to rush requests with a sense of urgency as needed.
  • Reviews invoice calculations, timesheets, expenses, sales tax etc.
  • Ensures payments are made in a timely fashion.
  • Identify and document non-compliant invoices.
  • Resolve invoice discrepancies directly with vendors and maintaining good vendor relations.
  • Provide general ledger account coding for all invoices.
  • Assist with 1099 process and vendor maintenance.
  • Distribute invoices to approvers for payment authorization.
  • Assist with current AP workflow and provide input to ensure process is increasingly efficient.
  • Vendor maintenance support including adding and updating information and cleaning of data.
  • Ensure W9 or W8BEN for is received for all vendors.
  • Prepare weekly domestic international wires.
  • Process weekly payment cycle.
  • Maintain excellent communication and relationships with key stakeholders.
  • Assist with quarterly accruals.
  • Follow SOX internal controls and established processes.
  • Ad hoc reporting and related projects, as requested.

Required Qualifications and Background

  • 5+ years in accounts payable or relevant finance experience within a SOX controlled environment.
  • Biotech, startup, or pharmaceutical experience a plus.
  • Experience with any SaaS (cloud based) accounting systems a plus.
  • Degree in accounting a plus.
  • Experience and ability to work in fast-paced environment.
  • Excellent interpersonal and communication skills (written and oral).
  • Strong organizational skills with amazing attention to detail.
  • Strong IT acumen with ability to work across multiple platforms and paperless AP environments.

Physical Demands / Travel

The physical demands of this position are consistent with light office duties.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

South San Francisco, CA

Reports To:

Executive Assistant

Position Summary

This position provides administrative and secretarial/receptionist support for the South San Francisco office, the Executive Assistant and staff. In addition to typing, filing and scheduling this position performs duties such as coordination of meetings and conferences, obtaining supplies, coordinating direct mailings and working on special projects.  Other duties include answering non-routine correspondence and assembling highly confidential and sensitive information. This position interacts with a diverse group of important external callers and visitors as well as internal contacts at all levels of the organization. Independent judgment is required to plan, prioritize and organize a diversified workload and recommend improvements in office practices or procedures.

Roles and Responsibilities of the Position*

  • Must be able to work from 8:30am-5pm Mondays through Fridays.
  • Schedules and organizes complex activities such as meetings, travel, conferences and department activities.
  • Acts as receptionist for company and greets outside visitors as needed.
  • Establishes, develops, maintains and updates filing system for the Vice President and the department. Retrieves information from files when needed. Establishes, develops, maintains and updates library of trade journals and magazines.
  • Organizes and prioritizes large volumes of information and calls.
  • Sorts and distributes mail. Drafts written responses or replies by phone or e-mail when necessary. Responds to regularly occurring requests for information.
  • Answers phones as needed. Takes messages or fields/answers all routine and non-routine questions. Works in cooperation with other assistants to cover phones.
  • Works both independently and within a team on a range of ongoing and on-off special projects. Acts as project manager for special projects, as needed, which may include: planning and coordinating multiple presentations and disseminating information.

Required Qualifications and Background

  • B.A. degree preferred with at least 3+ years of administrative support in smaller companies.
  • Professional demeanor and appearance and an excellent written and verbal communicator.
  • Detail oriented and well organized.
  • Able to work within a fast-paced environment adept at juggling multiple tasks and priorities.
  • Good and thoughtful listener.
  • Willing collaborator.
  • Enthusiastic, self-motivated and keen to improve processes and overcome inefficiencies.
  • Proficient in Microsoft Office suite and applications

Physical Demands / Travel

The physical demands of this position are consistent with light office duties.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

South San Francisco, CA or Stamford, CT

Reports To:

Clinical Data Management

Position Summary

The Clinical Data Coordinator is responsible for performing clinical data management tasks from study start-up through eTMF archiving for clinical trials. This individual collaborates with the Clinical Data Management (CDM) study leads, Clinical Trial Managers, (CTM’s) and Biostatistics team to perform data review and cleaning, database auditing, QC of import and exported data transfer deliverables, and ensures that all actions are in compliance with standard operating procedures (SOP) and regulatory agency guidelines.

This is an office based role at the Loxo office in either South San Francisco, CA or Stamford, CT with limited telecommuting allowed.

Roles and Responsibilities of the Position*

  • Performs routine and critical data review to ensure quality and identify data trends/issues.
  • CRF completion guidelines review; data management plan (DMP) review and execution; data reconciliations; edit check specifications review.
  • User acceptance testing (UAT) of electronic data capture (EDC) database, edit checks, reports and listings, et al, and interactive X response systems (IxRS) as needed. Work with external groups, including CDM contract research organizations (CRO), laboratories, and clinical trials centers to track toward established study milestones and timelines for the delivery of clinical and external data.
  • Contributes to the development of, implementation of and compliance to SOPs, work instructions (WIs) and guidelines regarding CDM.
  • Other duties as assigned.

Required Qualifications and Background

  • Bachelor’s degree in life sciences, math, computer science or related field required.
  • Minimum of three to five years clinical data management experience.
  • Thorough knowledge of data cleaning process and tactics for EDC clinical data and external data integration.
  • Experience executing independent UAT.
  • Oncology research experience is preferred.
  • Knowledge of regulatory guidelines such as GCP and 21 CFR Part 11.
  • Awareness of study data tabulation model (SDTM).
  • Awareness of CDASH and CDISC standards.
  • Certified Clinical Data Manager (CCDM) certification preferred.
  • Must be proficient in MS Office Suite and research EDC systems.
  • Must have excellent verbal, written and communication skills.
  • Ability to work independently as well as in a team environment.
  • Excellent time management skills and a proven ability to work on multiple projects at any given time in a fast-paced environment.
  • Demonstrated ability to stay abreast of trends and new information in the profession.

Physical Demands / Travel

This position will travel occasionally; the average travel for this position is 10% with some variation based upon the demands of the business imperatives.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a standard office environment.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Department:

Clinical Operations

Location:

Stamford, CT

Reports To:

Associate Director or Director, Clinical Operations

Position Summary

The Clinical Research Associate, in collaboration with the Clinical Trial Manager, contributes to the operational execution of clinical studies to ensure delivery on time, within budget, and of high quality in compliance with ICH/GCP, Regulatory Authorities’ regulations/guidelines, and applicable SOPs/WPs. Responsibilities may include participation on one or more cross-functional study team(s) and/or performance and quality oversight of one or more Contract Research Organization (CRO) teams and vendors.

Roles and Responsibilities of the Position*

Project Management:

  • Provide operational input on development, management and maintenance of study deliverables [i.e. timelines, study plans, documents, etc.] through collaboration with internal and external stakeholders.
  • Use performance metrics and quality indicators to assist the Clinical Trial Manager in driving study execution.
  • Participate in monitoring visit report review process to maintain oversight of clinical monitoring quality and adherence to protocol and established processes and plans.
  • Support Health Authority inspections and CQA audits as required.
  • Ensure full compliance (completeness and accuracy) of the required data in study management tools including clinical trial management systems, patient enrollment forecasting, etc.
  • Provide proactive identification of potential risks and develop and implement actions to avoid or mitigate.
  • Develop and maintain collaborative relationships with internal and external partners/stakeholders.

Study Planning and Conduct:

  • Collaborate with vendors and Loxo CTM’s regarding study specific issues and follow through to resolution.
  • Assist in the creation and review of study documents, including but not limited to the Protocol, Protocol Synopsis, Informed Consent Form (ICF) and other patient facing materials and assist in updating these study documents as needed.
  • Participate in vendor specification development and management/oversight.
  • Assist with management of TMF set-up, ongoing quality review, and final reconciliation.
  • Assist with shipment and reconciliation of Investigational Product (IP) at study and site level as needed.
  • Actively contribute to study meetings including presenting as a subject matter expert, generating, finalizing and distributing study team agendas and recording meeting minutes as needed.
  • Contribute to development/coordination of study training and study training materials for study team, investigational sites, and vendors.
  • Contribute to oversight of the required country regulatory (e.g. CTA, MoH) and country/site IRB/IEC submissions/approvals/notifications.
  • Assist with the collection of various study documents such as country/site insurance, CSR appendices, etc.
  • Assist with investigator meeting coordination and planning.

Required Qualifications and Background

  • Degree in a relevant discipline with experience in the Clinical Trial environment required.
  • Knowledge of ICH/GCP and regulatory guidelines/directives.
  • Demonstrates analytical approach and anticipation of problems.
  • Identifies gaps and provides constructive feedback and solutions.
  • Ability to multi-task effectively and prioritize assignments from multiple sources.
  • Basic knowledge of clinical research budgets including processing and tracking of site and vendor payments.
  • Knowledge of study tools including electronic system skills such as CTMS / EDC/ IRT/eTMF.
  • Knowledge of drug development process.
  • Proactively shares information, ideas, input, and/or expertise with team members.
  • Demonstrates concern for high quality outcomes.
  • Responds flexibly to changing business demands and opportunities, proactively looks for ways to contribute.
  • Basic understanding of project management desired.
  • Strong knowledge of MS applications including (but not limited to) MS Project, Word, Excel, PowerPoint.
  • Strong oral and written skills with proficiency in English.
  • Excellent organizational skills

Physical Demands / Travel

This position may require up to 25% travel. Some of the travel may be international.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in the field and in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT or South San Francisco, CA

Reports To:

Senior Director, Clinical Development & Medical Affairs

Position Summary

This position offers the opportunity to participate in the entire spectrum of the drug development process. Loxo designs drugs “from the ground up” by selecting a target we hypothesize is critical for cancer survival and producing a highly potent and specific inhibitor of that single target. This role is integral in moving this drug “from the bench to the bedside”, from initial planning of the first-in-human clinical trial to the pivotal studies necessary to prove its clinical efficacy and gain regulatory approval. The Clinical Scientist will participate directly in improving the lives of people fighting their cancers.

Roles and Responsibilities of the Position*

In tandem with the Medical Director this role designs, implements and executes Phase 1, 2 and 3 clinical trials for ultimate culmination in clinical study reports and NDA/MAA submissions. Excellent communication skills are important, as the position interacts with a variety of collaborators, including colleagues, outside consultants, clinical research sites, and key opinion leaders.

Loxo is a small company highly focused on clinical and regulatory execution. As a key member of the team, the Clinical Scientist will have the opportunity to work and learn in a fast-paced, team-oriented and exciting work environment that will literally change the lives of cancer patients for the better.

The Clinical Scientist will help translate preclinical discoveries into developing the next generation of cancer therapies and will be responsible for the design, implementation, and monitoring of clinical development programs. These programs include early proof of concept through registration in a variety of targets and may involve collaborations with corporate development partners. Responsibilities encompass strategic planning to ensure optimized clinical development plans for assigned projects. This individual must be interested in working in a fast-paced, team-oriented environment and be adaptable to rapidly changing priorities.

  • Serve as the clinical science representative on global and regional clinical execution teams.
  • Creates and fosters strong strategic partnerships with colleagues that include Clinical Operations/Development, Global Regulatory Affairs, Clinical Pharmacology, Statistics, Medical Affairs, Data Management and pre-Clinical Development.
  • Lead the design, implementation, operations/study management and interpretation of clinical trials.
  • Lead the writing of protocols, informed consent forms, clinical study reports and regulatory-related documents.
  • Work closely and liaise regularly with clinical sites and investigators to ensure implementation of clinical studies.
  • Review, interpret, and present clinical data from development program and the relevant literature at relevant scientific meetings.
  • Support the writing of subsequent regulatory briefing documents.
  • Lead and be accountable for study start up activities, site initiation visits, interpretation of interim data analyses, clinical data review, and preparation of dose escalation meetings.
  • Ensure trials are conducted effectively, reach target enrollment, and are conducted within budget and time-constraints, in partnership with CROs and Loxo regional and in-country groups, to deliver submission-quality data.
  • Demonstrate efficiencies in the areas of budget management, contracting and resourcing.
  • Demonstrate substantial and relevant knowledge of scientific and medical literature in oncology and its application to strategic design and operational achievements.
  • Work with external experts to develop abstracts, manuscripts, study/program design and presentations.
  • Apply scientific and operational knowledge to identify and analyze problems and information of considerable complexity and implement effective plans and solutions.
  • Ability to prioritize effectively and meet multiple deadlines successfully with attention to detail, setting high performance standards.
  • Proactively generate ideas for improvements and act to solve problems and achieve goals beyond what is required.

Required Qualifications and Background

  • PhD, PharmD or M.D.
  • The ideal candidate will have 5 years of biopharma experience in an academic or industry setting and at least 2+ years medical/clinical scientist experience in oncology. At least 5 years clinical research experience preferred, particularly in drug development in oncology.
  • Clinical trial expertise with experience in oncology with drug development highly desirable.
  • Must possess a strong background in clinical trials in an academic or industry setting.
  • Extensive academic/industry experience in laboratory-based cancer research or clinical trials is preferred.
  • The skills required for success in the job include scientific and analytic ability, ability to think strategically and tactically, an interest in applied clinical research, an ability to work effectively in multifunctional teams and excellent organizational and communication skills.
  • The candidate must demonstrate proven ability to evaluate, interpret and present complex scientific data to both technical and non-technical audiences.
  • Travel up to 20%, may include international travel

In summary, qualities sought include: intrinsic motivation, excellent communication and organizational skills; a passion for biomedicine and for patients; broad prior experience in drug development; and a comfort and desire to learn new skills.

Physical Demands / Travel

This position requires approximately 20% travel, which will fluctuate as business imperatives change.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in the field, occasionally in a lab and within a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Department:

Clinical Operations and Project Management

Location:

Stamford, CT or South San Francisco, CA

Reports To:

Director Clinical Operations

Position Summary

The Clinical Trial Manager functions as the clinical study team leader to plan, organize, and coordinate all operational aspects of a clinical study from protocol development through database lock. Ensures timely conduct of clinical studies according to protocols, Good Clinical Practice (GCP), Standard Operating Procedures (SOPs), and all applicable regulations governing the conduct of clinical trials.

Roles and Responsibilities of the Position*

  • Prepare and finalize project and study- related documents including: informed consent forms, clinical trial outlines, monitoring plans, synopses, protocols and amendments, IND annual updates and clinical summaries, as required.
  • Select investigators and study sites.
  • Identify and respond to site and study related issues and recommending corrective actions and/or escalating to supervisor.
  • Coordinate the design, format and content of CRFs, study guides, study reference binders, patient diaries, and forms including participating in the EDC and IVRS specification process and UAT.
  • Ensure that CRF data queries are resolved.
  • Coordinate and manage Investigational Product including overall accountability and reconciliation.
  • Prepare study budgets and timelines.
  • Manage project timelines and vendor performance to meet departmental and corporate goals.
  • Manage study budget and payment process for all clinical trial vendors including investigative sites.
  • Monitor and track clinical trial progress and provide status update reports.
  • Manage all clinical trial vendors (e.g., IVRS, central labs, and IRB).
  • Responsible for selection of CRO study staff and coordinating training including documentation.
  • Hire, train and oversee study field monitors (e.g., review of all trip reports) and provide guidance on site issues.
  • Lead with minimal supervision in the planning of investigator meetings and making presentations, as required.
  • Lead the review of clinical data at the CRF, data listing, and report table levels.
  • Represent Clinical Operations at the project team level for individual studies, as appropriate.
  • Partner with other research and development groups to achieve deliverables.
  • Participate in Site Initiation Visits (SIVs) as required.
  • Co-monitoring of regional sites for adherence to protocol and GCP as required.
  • Travel as required to carry out responsibilities.
  • Identify and escalate site, vendor and study related issues to supervisor, as appropriate.
  • Participate in clinical and department settings, including attending additional meetings as required, interacting in a positive and professional manner.
  • Manage Clinical Trial Assistants and Clinical Research Associates, and perform performance appraisals.
  • Perform other duties as assigned.

Required Qualifications and Background

  • BA/BS in related field.
  • Minimum 8 years clinical drug development experience.
  • Experience in personnel management.
  • Experience in CRO selection and management, including drafting request for proposals (RFPs), bidding process, etc.
  • Experience in managing oncology clinical trials (international preferred).
  • Knowledge of FDA regulatory requirements and medical practice/techniques and terminology.
  • Ability to work within a team, including leadership skills.
  • Ability to organize and prioritize multiple tasks.
  • Excellent communication and interpersonal skills.
  • Attention to detail, organization, and problem-solving skills.
  • Proficient in MS Office.

Physical Demands / Travel

This position requires approximately 25% domestic and international travel.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical field and office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Boulder, CO

Reports To:

Executive Director, Drug Discovery

Position Summary

LOXO Oncology’s newly formed Discovery group in Boulder, Colorado has an immediate opening for a leadership position in Computational Chemistry. The LOXO Discovery group’s mission is to invent and advance life-changing oncology drugs for cancer patient populations that are poorly treated by existing therapies. To that end, we are building a multi-disciplinary team of dedicated discovery scientists that are passionate about driving the science forward to create and advance highly selective drugs for known oncogenic drivers. We are currently looking for seasoned computational chemistry leader who enjoys tackling cutting edge drug discovery problems and is well versed in the effective use of all current computational techniques and tools. The ideal candidate will be passionate about working with scientists across disciplines to invent and advance novel approaches to drug discovery. The position requires excellent people skills, a positive can-do attitude and the ability to thrive in a highly interactive, fast-paced, team environment.

Roles and Responsibilities of the Position*

  • Work closely with our multidisciplinary group on structure-based and ligand-based design and optimiztion of small molecule oncology drugs.
  • Enable team success by employing a using a range of modern computational techniques including Quantitative Structural Activity Relationship (QSAR) models, homology modeling, solution simulation, multivariate analysis, and in silico predictive models.
  • Provide computational chemistry insight for new target identification and evaluation initiatives in the oncology space across a range of target and binding mode types.
  • Catalyze new hit and lead discovery leaning computation insight to selection of screening collections, database mining and interpretation of results and virtual screening techniques.
  • Implement and maintain the necessary hardware, software and infrastructure to enable a state of the art computational impact on the program.
  • Proactively investigate new or different technologies to improve the effectiveness of the team.
  • Contribute to the overall strategic thinking for the discovery organization.

Required Qualifications and Background

  • Ph.D. in Chemistry or related field.
  • 15+ years of experience in small molecule drug discovery experience in biotechnology or pharmaceutical setting.
  • Proven track record of success in advancing programs from lead to drug candidate.
  • Extensive experience in small molecule drug discovery across a range of target types, approaches and drug discovery strategies.
  • Possess a working understanding of medicinal chemistry, in vitro and in vivo ADME and couple that with modeling driven approaches that extend to aspects of lead optimiztion beyond potency.
  • Forward thinking in terms applying modern computation approaches to current scientific challenges. Apprised of the latest scientific breakthroughs in computational chemistry and ability to apply those techniques to good effect.
  • A key thought leader on the team. A passion for bringing creative approaches to fruition.
  • Excellent interpersonal skills with ability to communicate synergistically with a multidisciplinary team, the LOXO executive team and outside collaborators. The ability to lead the team in prioritization of activities and programs.

Physical Demands / Travel

The physical demands of this position are consistent with light office duties. The role may require up to 10% travel.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT

Reports To:

Executive Director, Commercial

Position Summary

Reporting to the Executive Director, Commercial, The Director / Senior Director, Commercial Operations will build a best-in-class biotech operations department to support the launch of several exciting new oncology drugs. The Director / Senior Director will be responsible for a wide variety of projects across the commercial and medical organizations to include functioning as the business lead for operational implementation of field facing systems and incentive compensation.

Roles and Responsibilities of the Position*

  • Responsible for all services and infrastructure needed to proactively support sales, marketing, reimbursement, and medical affairs.
  • Build out and oversee operations systems and functions to ensure timely and accurate collection, analysis, and reporting of data.
  • Build and maintain strong rapport with sales management and key customers to ensure ongoing needs are met.
  • Implement medical and sales field force sizing and deployment strategies to ensure Loxo portfolio objectives are appropriately achieved.
  • Sponsor CRM / field automation and decision support system implementation and upgrades. This includes identifying business requirements and approving design elements, user acceptance testing, and training. Identify and partner with third-party service providers for appropriate functions.
  • Maintain appropriate vehicle selectors for field personnel and ensure cost effective operation of fleet.
  • Facilitate the design and ongoing administration of incentive compensation plans for sales colleagues and MBO plan management for market access field management. Ensure plans motivate field personnel and support the commercial objectives for marketed products. Design and be part of the internal field compensation committee.
  • Implement effective customer targeting and reporting tools to support on-going sales promotion and assist management in evaluating sales productivity/performance.
  • Ensure sampling policies and practices comply with all laws and regulations.
  • Manage department budget and perform annual business planning. +Manage operations colleague(s) responsible for activities including:
    • Planning and logistics for sales meetings / POAs.
    • Field force communications and inquiry management.
    • Review committee process management (using Veeva PromoMats or other system).
    • Managing meetings and conventions logistics (i.e. securing space, booth development, vendor to management).
    • Production, inventory management, and fulfilment/shipping of sales and marketing materials.
    • Speakers bureau development and management.
    • HCP engagement contracting / compliance champion.
  • Co-lead operational design and implementation of field metrics to support Medical Affairs team members, Medical Science liaisons, and National Account Directors.
  • Work collaboratively with analytics team to develop tools and dashboards that capture key performance metrics.
  • Monitor the organization’s compliance with required standards for maintaining CRM data.
  • Ensure timely and accurate collection, analysis, management and dissemination of all field sales report.
  • Responsible for submission and maintaining compliance reporting (i.e. Sunshine Act reporting).

Required Qualifications and Background

  • Bachelor’s Degree in Business/Marketing, Accounting, Computer Science or related field—MBA preferred.
  • Minimum of seven years of biotech/pharmaceutical operations management experience, including sales operations.
  • Experience hiring high-performing operations team members and establishing the infrastructure needed to ensure readiness for a first commercial drug launch.
  • Strong knowledge of pharmaceutical sales data and systems including Veeva CRM.
  • Experience with the launch of new sales organizations and products and the development and implementation of field force deployment strategies.
  • Extensive experience with the development and implementation of national incentive compensation plans.
  • Skilled at communicating complex concepts to senior leaders/field colleagues.
  • Strong analytical skills with the capability to appropriately define issues, questions and data needs.
  • Experience managing third-party providers.
  • Demonstrated skills in interdependent team leadership. Highly developed decision-making and leadership skills.
  • Proven ability to direct multiple projects effectively.
  • Proficient with Microsoft Office.

Physical Demands / Travel

This role requires approximately 20% travel. Otherwise the demands of this role are consistent with light office duties.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in the field and in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT

Reports To:

Executive Director, Commercial

Position Summary

Reporting to the Executive Director, Commercial, the Director, Commercial Analytics will build a best-in-class biotech data management, analytics, and forecasting function to support the launch of several exciting new oncology drugs. The Director will work across key commercial functions to acquire, integrate, and manage data and to deliver analytical support and KPI reporting to help guide business decisions and support go-to market strategies.

Roles and Responsibilities of the Position*

These may include, but are not limited to:

  • Master Data Management (MDM) – responsible for set-up and administration of all aspects of MDM, including data feed integrations (sales data, specialty pharmacy data, claims data, HUB feeds) database queries and developing reports, etc.
  • Establishing data integrity controls to ensure accuracy in support of data driven decision making.
  • Assisting Commercial Operations in the acquisition of product performance data necessary to support the establishment of a KPI-measurement plan, which provides useful and timely data on diagnostic testing adoption and product uptake to the field sales organization and cross-functional leadership teams.
  • Engage with Marketing, Sales, Market Access, and Medical to understand each strategic initiative and corresponding data needs including CRM and/or secondary data generated insights.
  • Build and oversee monthly patient-flow forecast model and contribute market data/insights to guide critical forecast assumptions; develop process and dashboards to track revenues to forecast on a weekly and monthly basis.
  • Collaborate with Finance and Market Access to share information for gross-to-net forecasts and other key financial assumptions and ensure all forecasts are completed with the highest level of diligence and precision.
  • Develop annual sales budgets, with periodic (e.g., quarterly) re-forecast updates.
  • Assist Commercial Operations with administration of the sales incentive compensation program by updating territory/regional/national metrics on a frequent basis and disseminating the data via representative facing applications.
  • Contribute to critical business planning initiatives, including; long-range planning, brand planning, launch planning, business development initiatives, forecasting and valuations.
  • Ensure all analytics contracts, service agreements and rates are efficient and compliant with company policies.
  • Potential to oversee, either directly or via an FTE report, primary market research planning and activities, including:
    • Collaborate with Marketing, Market Access, and Medical to develop a comprehensive market research plan to optimally support product launch.
    • Design/execute qualitative and quantitative market research work streams, working closely with commercial team members to ensure all desired learnings and insights are attained.
    • Develop process for and deliver regular and real-time monitoring of competitive & market intelligence.
    • Manage budgets and vendors for market research projects per company guidelines.

Required Qualifications and Background

  • BA/BS required with a minimum of 7+ years of pharmaceutical/biotech experience in increasing roles of responsibility; advanced degree highly desirable.
  • Extensive knowledge of and experience in commercial analytics (including forecasting and sales analytics) and master data management is required.
  • Experience in oncology and/or rare disease required; experience managing and analyzing specialty pharmacy data feeds required.
  • Must have experience executing pharmaceutical incentive compensation programs.
  • Experience managing primary market research plans, projects, and vendors preferred.
  • Previous experience supporting marketing, sales, medical affairs and strategic planning functions.
  • Proven experience evaluating and selecting secondary data and market research vendors, as well as business intelligence tools required.
  • Ability to convert analytical findings to market insights so that they are clear and concise to any audience is necessary.
  • Strong spreadsheet/database analytical skills and advanced Excel and PowerPoint required.
  • Ability to lead and mobilize cross-functional working groups and project teams.
  • Excellent analytical, writing and presentation skills are essential.
  • Ability to prioritize and oversee multiple projects in a fast-paced, fluid environment.
  • Must be highly organized, detail-oriented and results-driven.
  • Must be proficient in Microsoft Office suite.

Physical Demands / Travel

Ability to travel domestically and internationally as the position requires.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in the field and in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT or Remote

Reports To:

Executive Director, Market Access

Position Summary

The Director, National Accounts, reporting to the Executive Director, Market Access, will be responsible for developing relationships with leading national, regional, and local payers as well as channel decision-makers. This individual will develop and manage their accounts to attain key objectives for the Loxo Oncology product portfolio. The Director, National Accounts will implement short and long-term strategic initiatives to ensure appropriate coverage, coding, and payment within their managed market accounts.

Roles and Responsibilities of the Position*

  • Spearhead payer (commercial, Medicare, Medicaid) profiling effort pertaining to coverage policies of third party payers.
  • Analyze market access related challenges, barriers and opportunities for Loxo Oncology products.
  • Provide clear examples of overcoming payer barriers/objections in the targeted therapy/oncology space.
  • Monitor and address payer activity with respect to companion diagnostics and genomically-targeted oncology therapies.
  • Assess product positioning and develop strategic plans for channel customers who may include commercial payers, PBMs, IHNs/IDNs, IPAs, ACOs and other account targets.
  • With Market Access leadership, develop short and long-term business planning that addresses overall corporate and brand initiatives and goals. Work with manager to track progress against goals.
  • Ensure on-label coverage policies and appropriate formulary/tier placement.
  • Responsible for developing strong account relationships at an executive level with medical director, pharmacy director, as well as personnel from pipeline and actuary department.
  • Educate managed care customers about the disease state and product portfolio
  • Analyze and identify alternative contracting options or account engagement opportunities when appropriate.
  • Conduct regular business reviews to identify and provide updates on business opportunities.
  • Coordinate with various departments to develop and implement timely launch activities with payers. Coordinate and present payer value proposition and customer solutions to ensure optimal coverage.
  • Work closely with internal stakeholders (i.e. field sales staff) and external stakeholders (Provider, HUB, SP) to provide training on relevant reimbursement and payer issues (provider and payer trends, current market access landscape, competitive intelligence, positioning, etc.).
  • Serve as liaison for local managed care and reimbursement activities, including reimbursement hub services.
  • Represent the Market Access organization and company at identified national payer organizations and other industry associations or entities.
  • Develop strategic relationships with state oncology societies.
  • Ensure compliance with legal and regulatory requirements with respect to market access and reimbursement.
  • Manage timelines, costs, resources, and report status to management.
  • Other special projects as assigned.

Required Qualifications and Background

  • A minimum of 5 years’ experience managing national and major regional payer accounts (Commercial, Medicare, and Medicaid) and leading successful contract negotiations.
  • Experience in managing key customers in the Managed Care, Oncology GPO and Specialty arena. Must have account relationships established.
  • Oncology or specialty care pharmaceutical product experience is required.
  • Bachelor’s degree is preferred and/or equivalent work experience.
  • Sales or sales management experience highly desirable.
  • Demonstrated knowledge of payer decision-making for policy, coverage, coding and patient access to existing and new products.
  • Ability to create and present strategic business plan to senior level managers both internally and to customers.
  • Strong management, organizational, communication, negotiation, and business development skills.
  • Demonstrated ability to manage budget and resources.
  • Team player who can successfully collaborate with other account team members and across all commercial and field team members.
  • Demonstrated effectiveness operating in a field-based position with proven ability to work independently, adhere to specific timelines, deliver on administrative responsibilities, and execute business planning and initiatives.
  • Knowledge and ability to perform all company business in accordance with all regulations (e.g. EEO, FDA, DEA, OSHA, PDMA, EPA, PhRMA, etc) and company policies and procedures. Report noted/observed violations immediately to management. Demonstrate high ethical and professional standards with all business contacts to maintain the company’s excellent reputation within the medical and pharmaceutical community.
  • Proficiency in MSOffice, Outlook and database applications, including knowledge of various desktop applications.
  • Experience in Cognos/Report writing toolset required.

Physical Demands / Travel

This position requires up to 70% travel (50-60% field, 5-10% corporate office based).

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in the field and in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT

Reports To:

CEO

Position Summary

Loxo Oncology is seeking to establish a world-class compliance program. We seek an individual to help build and establish the corporate compliance function to enhance the company’s strong culture of compliance. Reporting directly to the Chief Executive Officer, the Head of Compliance will work collaboratively and strategically with our leadership to drive a culture of ethics, integrity and compliance across the Loxo organization. This position will have the opportunity to partner with the corporate leadership team on both the strategic and operational direction of business, and provide guidance on opportunities and challenges that may be forecasted.

Our compliance function will be accountable for establishing, monitoring and continuously improving Loxo’s Compliance Program. This will include defining compliance standards via policies and procedures, compliance training and communications, auditing and monitoring, facilitating internal reporting, conducting compliance-related investigations, and informing Executive Leadership and the Board of Directors of compliance matters.

Roles and Responsibilities of the Position*

  • Evaluate and establish company policies, SOPs, guidelines, and associated internal communication and training plans related to key areas of risk relevant to global pharmaceutical companies.
  • Design and deliver compliance-related training, including new hire training, code of business conduct and ethics training, and policy-related training.
  • Design and manage the company’s compliance with state and federal aggregate spend reporting and disclosure laws requiring specific compliance program elements, including implementation of the appropriate systems.
  • Design and perform compliance monitoring activities to prevent, monitor and detect compliance-related issues.
  • Oversee company trading policy and administer trading review process.
  • Develop and execute risk assessments and reviews of compliance risk areas to determine need for improvement.
  • Counsel and provide leadership with business partners on compliance and compliance process issues.
  • Perform or collaborate in performing investigations of potential compliance issues.
  • Work closely with executive leadership to ensure appropriate risk management.
  • Oversee compliance hotline.
  • Periodically review and update the code of business conduct and ethics to ensure continuing relevance in providing guidance to management and employees.
  • Maintain high level of knowledge of current and emerging laws and regulations and recent enforcement actions and inform and educate business units with tailored communications.

Required Qualifications and Background

  • Candidates should have strong academic credentials as well as 6 to 15 years of experience in a law or consulting firm setting advising or counseling pharma or biotech clients, or in an in-house pharma or biotech setting.
  • Knowledge of laws and regulations relating to prescription pharmaceuticals.
  • Outstanding written communication skills, with an ability to cogently and succinctly communicate complicated legal and compliance principles in a straightforward, understandable manner.
  • Strong presentation, influencing and collaboration skills.
  • Ability to communicate with all levels of management and employees, both in writing and verbally.
  • Possess sound, practical judgment in the interpretation and application of relevant laws, regulations, industry standards and company policies.
  • Excellent project management skills with the ability to organize and manage multiple priorities while meeting deadlines.
  • Self-motivated and able to work with minimal supervision; able to exercise sound judgment in resolving matters of high complexity and escalating matters appropriately.
  • Strong analytical and critical thinking as well as demonstrated accuracy and attention to detail.
  • Ability to handle multiple tasks in a fast-paced environment.
  • Confidence and professionalism to handle difficult conversations and discretion on sensitive matters.
  • Demonstrated strong commitment to and model of compliance, ethics and accountability.

Additional Preferred Qualifications

  • Experience drafting and implementing policies for a life sciences company.
  • Experience working across multiple countries.

Physical Demands / Travel

The demands of this position are consistent with light office duties.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT

Reports To:

TBD

Position Summary

The Head of Drug Safety is responsible for managing the safety surveillance program for investigational and post marketed products. The Head of Drug Safety is responsible for managing technical functions at a strategic level, playing a major role in shaping cohesive pharmacovigilance strategies through effective optimization and integration of operational and safety systems functions. This individual is responsible for the maintenance of structural organization within the department, as well as the technical and managerial coordination of its groups and staff.

Roles and Responsibilities of the Position*

  • Ensures standard processes and procedures for all aspects of pharmacovigilance including adverse event case handling, aggregate reporting and ensuring compliance with global and local regulatory requirements.
  • Demonstrates and applies advanced knowledge of safety concepts, per ICH, US and international guidelines and Good Pharmacovigilance Practice (GPvP).
  • Collaborates with safety systems associates ensuring Argus support of safety reporting, audits and inspections, aggregate reports, and signal detection.
  • Collaborates with internal and external stakeholders, including: Medical Affairs, Clinical, Regulatory, Quality Assurance, Marketing Partners, and CROs.
  • Responsible for the oversight of SOPs development and management plans/procedures needed for the Safety Group to execute its responsibilities.
  • Accountable for effective management of departmental resources, expenses and budget.
  • Supervises Operational and Safely Systems Personnel in the Drug Safety Department.
  • Provides expert pharmacovigilance guidance and leadership both internally and externally.
  • Responsible for oversight of quality, standards and training of personnel.
  • Responds appropriately to rapidly changing safety regulatory environment with minimal oversight.
  • Responsible for the oversight of regulatory queries concerning adverse event documentation.
  • Creates a talent management plan to address individual performance needs as well as establishes a succession plan for the team.
  • Ensures effective performance management process is in place and specific development plans implemented for each team member.

Required Qualifications and Background

  • M.D. or Doctorate level degree in health sciences is required.
  • Clinical experience as a Pharm.D. or M.D. required, including significant pharmaceutical industry safety surveillance with clinical expertise in Oncology.
  • Minimum of seven to ten years of progressive experience in Drug Safety in a biotechnology or pharmaceutical company required.
  • Prior experience in regulatory requirements and guidelines pertaining to Drug Safety and Pharmacovigilance required.
  • Advanced knowledge of safety concepts, per ICH, US and international guidelines and Good Pharmacovigilance Practice (GPvP) required.
  • Knowledge of U.S. and International Regulatory Reporting Requirements for Product Safety, and of the clinical development process.
  • Expertise in the use of MedDRA is required.
  • Strong operational skills as demonstrated by leading previous projects or functions and or equivalent in training and education in areas such as Lean Six Sigma or MBA preferred.
  • Must possess strong ability to communicate and integrate their work activities with co-workers, and to effectively organize and present ideas and results.
  • Must be proficient in MS Office Suite.
  • Expert knowledge of relational database applications (including Argus or other safety database).
  • Solid knowledge of safely database operations and functions.
  • Strong ability to prioritize tasks and keen attention to detail.
  • Excellent writing, communication, presentation, and interpersonal skills.
  • Demonstrated leadership and project management skills.
  • Ability to be both enterprising and resourceful.
  • Proven ability to work on multiple projects in a fast-paced environment.

Physical Demands / Travel

The physical demands of this position are consistent with light office duties. The role may require up to 15% domestic and international travel.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Boulder, CO

Reports To:

Executive Director, Drug Discovery and Executive Director, Discovery Biology

Position Summary

This position provides administrative and facility support for the Boulder, CO discovery facilities and staff. This role performs duties such as coordination of meetings and travel, detailing expense reports, identifying and contacting facility support contractors such as electricians and general maintenance, obtaining office and lab supplies, receiving supplies and lab equipment, assisting with lab equipment installation, and working on special projects including assisting with laboratory research.

The successful candidate will need to be a professional and successful communicator capable of coordinating with a diverse group of external callers, contractors, and visitors as well as internal contacts at all levels of the organization. Independent judgment is required to plan, prioritize and organize diversified workload, and we are looking for a hardworking, self-motivated individual with a willingness to identify inefficiencies and recommend improvements in lab and office practices.

Roles and Responsibilities of the Position*

  • Schedules and organizes complex activities such as meetings, travel, conferences and facility management activities.  
  • Must be able to work from 8:30am-5pm Mondays through Fridays.
  • Acts as receptionist for lab facility directing visitors to appropriate staff or location.
  • Receives office and lab deliveries inside, outside, and on a dock.
  • Coordinates the delivery and installation of specialized equipment with scientific staff.
  • Sorts and distributes mail.
  • Answers phones as needed.
  • Works independently and within a team on special non-recurring and ongoing scientific projects. These activities may include assisting with preparing presentations, performing laboratory experiments, inputting or cross-checking data, and organizing literature research.

Required Qualifications and Background

  • B.A. degree is preferred with an interest in providing administrative and facilities support.
  • Professional demeanor and an excellent written and verbal communicator.
  • Detail oriented and well organized.
  • Able to work within a fast-paced environment adept at juggling multiple tasks and priorities.
  • Good and thoughtful listener.
  • Willing collaborator.
  • Enthusiastic, self-motivated and keen to improve processes and overcome inefficiencies.
  • Proficient in Microsoft Office suite and applications.
  • Experience with supervising and directing contractors and outside vendors.

Physical Demands / Travel

  • Ability to lift 30 pounds on to a 3-foot table
  • Oversight of hazardous waste materials.
  • Ability to push a cart with 80 pounds from loading dock to destination in a lab or office.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

  • Brief exposure to outdoor weather to facilitate movement of items between lab site and dock.
  • Exposure to standard laboratory noise and environment.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

South San Francisco, CA

Position Summary

The Project Manager is responsible for supporting the development and execution of the product development project plan including timing and deliverables, to achieve project goals through a Cross-Functional Project Team. This position will support 1-2 of the portfolio projects in post-IND stage development. This role contributes to the definition of project strategy and guides the project core and sub-teams to deliver on project objectives.

Roles and Responsibilities of the Position*

  • Drive the development and execution of the product development plan – including costs, timing and deliverables.
  • Track functional milestones (CMC, Nonclinical, Clinical, Regulatory) and other sub team activities to ensure overall adherence to the project timeline.
  • Act as a primary contact for project team related information.
  • Prepare progress reports and ad hoc reports as required, identifying and anticipating issues that threaten a project’s adherence to the timeline.
  • Actively manage, in coordination with the Project Team leader, internal and external collaboration partners, and outside vendors, when appropriate.
  • Plan and facilitate Project Team and ad hoc functional meetings and ensure the proper conduct during those meetings (minutes, agendas, action items, etc.).
  • Provide support in resolving project issues by managing contingency planning and influencing risk mitigation strategies with input from various functions.
  • Participate in development of project management tools, templates and processes.
  • Respond to changing duties as responsibilities may vary based on potential pipeline growth, project needs, and stages of development.

Required Qualifications and Background

  • Bachelor’s degree in the Life Sciences. Advanced degree is desired.
  • Minimum 4 years of multi-disciplinary experience in the biotech/pharmaceutical industry.
  • Minimum 2 years direct project management experience in drug development with knowledge of the overall drug development process.
  • Alliance management experience a plus.
  • PMP (Project Management Professional) certification or equivalent is a plus.
  • Proven expertise in effectively applying the appropriate level of project management methodologies in the drug development setting.
  • Proficiency in use of MS Project, MS Word, Excel and PowerPoint software.
  • Demonstrated ability to work well with other accomplished professionals within and across functions/teams.
  • Willingness to travel domestically and internationally as required.
  • Ability to hold oneself and others accountable for commitments in a productive and assertive, positive (not aggressive) manner.
  • Strong communication skills both written and oral.
  • Ability to influence outcomes without direct authority.
  • Ability to multi-task and shift priorities rapidly to meet tight deadlines.

Physical Demands / Travel

The physical demands of this position are consistent with light office duties. The role may require up to 10% domestic and international travel.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Boulder, CO

Reports To:

Executive Director, Discovery Biology

Position Summary

This position offers the opportunity to be part of Loxo’s discovery teams focused on creating novel, highly specific and selective drugs for genetically identified targets. The Senior Structural Biologist will offer structural and mechanistic insights to a multi-disciplinary discovery team by providing high-resolution protein-ligand crystal structures.

Roles and Responsibilities of the Position*

  • Generate protein-small molecule complex x-ray crystal structures with hands-on lab involvement throughout the entire gene to structure process, including protein expression, purification, crystallization, and structure determination.
  • Coordinate protein construct design, expression, and purification with the project team to support biochemical and biophysical assays.
  • Rapidly communicate scientific results and insights to the team.
  • Set-up new laboratory facility with extensive involvement in equipment and supply evaluation, purchase, installation, testing and IT integration.
  • Identify, evaluate, and manage vendors for outsourced services and studies.
  • Collaborate with colleagues throughout the company to ensure structural work meets the program needs and results are appropriately interpreted.
  • Prepare reports for internal and external purposes including regulatory submissions.
  • Participate and lead project-based and technical team meetings to identify and solve problems, guide work towards project goals, communicate on-going work and progress, and plan forward thinking strategies.
  • Develop and continually advance one’s knowledge base on genetically targeted drugs and structure-based drug design.
  • Proactively investigate new or different technologies, methods, and service providers to ensure our work is being done in a scientifically sound, efficient, and reasonable way.
  • In the future, this position’s responsibilities may include supervision of scientists and associates.

Required Qualifications and Background

  • PhD in Biochemistry, Chemistry, or related field.
  • Ideal candidate will have with 5+ years hands-on gene to structure protein-small molecule crystallography experience in a biotech/pharma setting.
  • Highly skilled in crystallization of protein-small molecule complexes and high-resolution x-ray structure determination.
  • Extensive experience in protein construct design, expression, purification, and characterization.
  • Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels.
  • Highly organized with excellent analytical, documentation and multi-tasking skills.
  • Committed to staying current with the latest scientific breakthroughs in structure-based drug design and structural biology.
  • Expertise in other methods of biophysical and structural biology is a plus.

Physical Demands / Travel

Weekly local (within 25 miles) non-overnight travel may be required during certain phases of the projects. Occasional travel to meetings will be required.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based equally in a wet lab and office environment.

The work environment characteristics described here are representative of those encountered by an employee performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each of the responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now


Location:

Stamford, CT

Reports To:

Accounting Manager

Position Summary

The Staff Accountant role is a “hands on” position with direct responsibility for Loxo’s bank reconciliation, prepaid expenses, fixed assets, clinical trial and other R&D accounting, invoicing, purchasing, contract administration, and financial close responsibilities. This position reports to the Accounting Manager. This position will work directly with a wide range of individuals including senior management, finance team, clinical trial managers, vendors and CRO’s (contract research organizations). This individual must possess great attention to detail, meticulous organization skills, and a strong desire and ability to work within a dynamic, fast-paced environment with the expectations of the role consistently expanding.

Roles and Responsibilities of the Position*

Accounting close:

  • Record cash entries and perform bank reconciliations.
  • Evaluate invoices coded to prepaid expenses for accounting treatment, record prepaid expense entries and preform account reconciliations.
  • Evaluate invoices coded to fixed assets for accounting treatment, record depreciation expense entries, and perform account reconciliations and roll-forward.
  • Through general ledger review identify and record reclass entries and maintain general ledger.
  • Identify and record accruals from invoices and estimates provided by internal and external stakeholders.

Clinical Trials and other R&D Accounting:

  • Lead quarterly meetings with CRO, internal teams, and management to provide project updates and obtain validation of % of completion.
  • Prepare and maintain clinical trial reconciliations and prepare journal entries and accruals.
  • Maintain clinical accounting policies and procedures, recommending procedural changes when necessary.
  • Review clinical trial protocols and contracts to translate information to financial implications.

Accounts Payable:

  • Support accounts payable team in processing invoice transactions into accounts payable module and ensuring proper accounting treatment and coding is present.
  • Support accounts payable team in reviewing and analyzing invoices against contracts, purchase orders, quotes, investigate, resolve, and communicate discrepancies from this review to all stakeholders to ensure timely and accurate processing.
  • Review, analyze, and investigate invoice and statement calculations, supporting documents and tax treatment to resolve any discrepancies timely and accurately.
  • Assist with quarter-end close including preparation of invoice accruals and ad hoc reporting.
  • Ensure SOX compliance by identifying and resolving invoices that do not comply with the internal control framework.

Required Qualifications and Background

  • 3 - 5 years in accounting and relevant Finance experience within a SOX controlled environment.
  • Bachelor’s Degree in Accounting and Finance.
  • Clinical trial and other R&D accounting experience.
  • Biotech, startup, or pharmaceutical experience.
  • Strong excel knowledge.
  • Experience with any SaaS (cloud based) accounting systems a plus.
  • Experience and ability to work in fast-paced environment.
  • Excellent interpersonal and communication skills (written and oral).
  • Strong organizational skills with amazing attention to detail.
  • Strong IT acumen with ability to work across multiple platforms and paperless environments.

Physical Demands / Travel

The physical demands of this position are consistent with light office duties.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is based in a typical office setting.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Apply Now