Research Associate/Associate Scientist, Biophysics
Loxo@Lilly conducts discovery research, clinical development and regulatory affairs for oncology, with the goal of creating a pipeline of therapies that have the potential to make a meaningful difference for patients. Loxo@Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. The unit has team members in Louisville, CO, Indianapolis, IN, New York City, NY, South San Francisco, CA, San Diego, CA, Stamford, CT, and Madrid, Spain.
Loxo@Lilly's newly formed Drug Discovery group in Louisville, Colorado has an immediate opening for a researcher in Biophysics. The Loxo Drug Discovery group’s mission is to invent life-changing targeted therapies for cancer patient populations that are poorly treated by existing therapies. To that end, we are building a multi-disciplinary team of dedicated drug discovery scientists who are passionate about driving the science forward to create highly selective drugs for known oncogenic drivers.
The ideal candidate is self-motivated, responsible, and a productive scientist who enjoys collaborating with biologists, chemists, and assay scientists. In this role, he/she will utilize a variety of assay technologies including mass spectrometry, fluorescence spectroscopy, surface plasmon resonance, and isothermal titration calorimetry to evaluate protein/ligand interactions. Experience in protein purification and characterization is a plus. This position requires excellent people skills, a positive can-do attitude, passion for lab work, attention to detail, and the ability to thrive in a highly interactive, fast-paced, team environment.
Roles and Responsibilities of the Position:
- Prosecute biophysical assays to identify and characterize small-molecule modulators using a variety of techniques and detection methods, including chromogenic, MS, SPR, ITC, FP, FRET and TR-FRET
- Continuously expand our biochemical characterization repertoire by exploring and developing additional assay and technological instrumentation
- Calculate and report assay results to the project teams
- Document experiments and results in electronic notebook, and results database
Required Qualifications and Preferred Background:
- A BS or MS with 0-3+ years relevant work experience. Level commensurate with education and experience
- Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels
- Highly organized and detail oriented with excellent analytical, documentation, and multi-tasking skills
- Committed continual learner, who is accustomed to staying current with the latest scientific breakthroughs in structure-based drug design and biophysics
- Expertise in other methods of enzymology or biophysical characterization and structural biology is a plus
- Protein Purification and characterization a plus
Loxo Oncology, Inc. currently anticipates that the base salary for the Research Associate level position could range from between $50,000 to $73,370 and that the base salary for the Associate Scientist could range from between $59,000 to $86,577 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. This position will also be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Loxo provides a comprehensive benefit program to eligible employees, including vacation, medical, dental and vision benefits; participation in a 401(k) plan; life and accidental death and disability coverage; parental leave benefits and employee discounts for certain items. The compensation described above is subject to change and could be higher or lower than the range described.
The physical demands of this position are consistent with working in a laboratory/ bench environment. Some lifting, and maneuvering of equipment may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is based in a laboratory/ bench environment.
The work environment characteristics described here are representative of those an employee encounters while preforming the essential functions of this job.
*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo Oncology, Inc. is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).
Loxo Oncology, Inc. (“Loxo”) is committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Loxo, please email email@example.com for further assistance. Please note, this email address is intended for use to request an accommodation as a part of the application process. Any other correspondence will not receive a response.