Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by our goal of improving the lives of people living with cancer. We pursue this goal with a tenacity, focus, and commitment to excellence that defines who we are and how we work.
We seek dedicated, passionate, hardworking, intelligent, thoughtful, and authentic individuals who thrive within a collaborative and fast-paced environment and will bring their experiences, unique perspectives and problem-solving skills to the team. In return, we cultivate an environment that rewards and recognizes hard work and provides opportunities for learning and growth as part of a team making a meaningful difference in the lives of patients.
Head, CMC
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
Loxo Oncology chemical manufacturing controls (CMC) team has an immediate opening for an Associate Director/Director of Pharmaceutics. The individual will be responsible for all aspects of drug product formulations and cGMP manufacturing operations, including oversight of laboratory development work and analytical testing at external research, development, and manufacturing organizations (CDMOs).
Loxo Oncology is looking for an independent self-starter with experience designing and manufacturing solid oral dosage forms under cGMP. This individual will be responsible for the preparation of technical reports and drug product sections of CMC regulatory submissions. Experience with the design, development, and manufacturing of liquid and enabled formulations for compounds with low solubility is also highly desired.
The physical demands of this job are consistent with light office duties. This position requires up to 20% travel.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office with some traveling in the field.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Medical Affairs
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Associate Medical Director will contribute to the direction, planning, and execution of Expanded Access Programs (EAP) associated with one or more clinical development programs. Participates in and may lead cross-functional teams to generate, deliver, and disseminate high-quality clinical data supporting overall program, scientific and business strategy.
The physical demands of this job are consistent with light office duties.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Biostatistics
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
This position will serve as study statistician for Phase 1-3 oncology studies to support NDA submissions as well as coordinating activities with other functional groups to ensure timeliness and quality of study deliverables.
The physical demands of this job are consistent with light office duties.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Bioassay Screening
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Cell Biologist will be responsible for identifying, developing, and performing robust, reproducible cell assays to support drug discovery and development in a team environment. The Cell Biologists will provide hands-on compound testing to support the small molecule drug discovery oncology pipeline. The scientist fulfilling this position will be responsible for characterizing the effects of small molecule compounds on specific protein targets in cells using multiple plate-based assay formats examples include HTRF, ELISA, In-Cell Western, Mesoscale, and proliferation. A strong background in experimental curve-fitting, statistics, and assay optimization and execution is required.
The physical demands of this job are consistent with a lab.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in a lab.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Manager, Clinical Data Management
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Contract Clinical Data Manager is responsible for overseeing data management tasks from study start-up through database lock for clinical trials. This individual collaborates with the Clinical Trial Managers (CTMs), Biostatistics team, and data management vendors to ensure database development, data review/cleaning, database auditing, database lock, and receipt of final database deliverables are in compliance with standard operating procedures and regulatory agency guidelines. The Clinical Data Manager ensures all Clinical Operations activities stay within full compliance of Loxo regulatory and legal policies.The Contract Clinical Data Manager is responsible for overseeing data management tasks from study start-up through database lock for clinical trials. This individual collaborates with the Clinical Trial Managers (CTMs), Biostatistics team, and data management vendors to ensure database development, data review/cleaning, database auditing, database lock, and receipt of final database deliverables are in compliance with standard operating procedures and regulatory agency guidelines. The Clinical Data Manager ensures all Clinical Operations activities stay within full compliance of Loxo regulatory and legal policies.
This position will travel occasionally; the average travel for this position is 10-15% with some variation based upon the demands of the business imperatives.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
The position’s work environment is based in a typical office setting with occasional travel required.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Clinical Trial Operations Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Clinical Research Associate in collaboration with the Clinical Trial Manager, contributes to the operational execution of clinical studies to ensure delivery on time, within budget, and of high quality in compliance with ICH/GCP, Regulatory Authorities’ regulations/guidelines, and applicable SOPs/WPs. Responsibilities may include participation on one or more cross-functional study team(s) and/or performance and quality oversight of one or more Contract Research Organization (CRO) teams and vendors.
The physical demands of this job are consistent with light office duties. Up to 25% travel may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Clinical Operations Team Leader
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
Functions as the clinical study team leader to plan, organize, and coordinate all operational aspects of a clinical study from protocol development through database lock. Ensures timely conduct of clinical studies according to protocols, Good Clinical Practice (GCP), Standard Operating Procedures (SOPs), and all applicable regulations governing the conduct of clinical trials.
The physical demands of this job are consistent with light office duties. Up to 15% travel may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Clinical Trial Manager
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
CRA/Field Site Monitor will coordinate clinical studies and be responsible for all major stages of study development, execution, monitoring, and close-out. This individual will also be responsible for clinical study site maintenance, data and source documentation collection, as well as field monitoring of clinical trials. Duties will include ensuring compliance to the study protocol, and Monitoring Plan by ensuring completeness and accuracy of data as well as compliance with domestic and international regulations, Good Clinical Practices, applicable regulatory standards, and Standard Operating Procedures.
Physical Demands:
The physical demands of this job are consistent with light office duties
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This role can require up to 40% domestic and international travel
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position’s work environment is in an office.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
No specific work demands.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Medical Affairs
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Diagnostics Medical Science Liaison (DxMSL) is responsible for the identification and engagement of targeted groups of regional thought leaders within the pathology, laboratory, and oncology communities with specific responsibility for providing consistent delivery of educational and compliant scientific information surrounding clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing.
Please note this role will require up to 50% travel, primarily within assigned region but also nationally and globally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Medical Director, Medical Affairs
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Diagnostics Medical Science Liaison (DxMSL) is responsible for the identification and engagement of targeted groups of regional thought leaders within the pathology, laboratory, and oncology communities with specific responsibility for providing consistent delivery of educational and compliant scientific information surrounding clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing.
Please note this role will require up to 50% travel, primarily within assigned region but also nationally and globally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Drug Safety
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Drug Safety Specialist will be responsible for providing Drug Safety/Pharmacovigilance support for new and ongoing clinical trials including the collection, processing, and reporting of adverse events/endpoints while adhering to International Council for Harmonization (ICH) guidelines, Good Clinical Practices (GCP), applicable regulatory guidelines, data protection guidelines and study procedures.
The physical demands of this job are consistent with light office duties.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Bioassay Screening
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Enzymology Scientist will be responsible for developing and performing robust, reproducible enzyme and binding assays to support drug discovery and development in a team environment. The scientist fulfilling this position will be responsible for characterizing the effects of small molecule compounds on specific protein targets. A strong background in experimental curve-fitting, statistics, and assay optimization and execution is required.
The physical demands of this job are consistent with a lab.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in a lab.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Principal Research Scientist
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Lab Coordinator will provide critical support in a robust discovery biology lab environment through inventory tracking, lab organization, supply ordering, materials information tracking, data entry, and additional lab responsibilities. The Lab Coordinator will possess excellent organization, clear communication, eagerness to learn, and adaptability.
The physical demands of this job are consistent with light office and wet-lab duties. Requires ability to lift 20 lbs.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in a lab.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Associate Medicinal Chemist
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Lab Operations Coordinator will support a robust Discovery Lab environment through sample preparation, sample organization and tracking, data entry, safety maintenance, and additional responsibilities as needed. The Lab Coordinator will possess excellent information management skills as well as the ability to communicate, explain, interpret, and share information in order to best support the Discovery team.
The physical demands of this job are consistent with working in a wet-laboratory setting. Requires ability to lift up to 15 lbs.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in a lab.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Manager, Talent Acquisition
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Senior Recruiter/Manager, Talent Acquisition will play a pivotal role in our growing organization. Based in our South San Francisco office, this individual will manage full life cycle recruitment for open requisitions, while assisting in further developing recruitment processes. In collaboration with Human Resource partners, Leadership and Hiring Managers the Senior Recruiter will focus on establishing skill requirements, background and experience needed, for open requisitions across Discovery, Pre-clinical and Early-phase clinical development. Further, the Senior Recruiter will be tasked with telling the Loxo story with an emphasis on culture and our guiding principles of strong science coupled with patient focus.
The physical demands of this job are consistent with light office duties.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, Medical Affairs
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
This individual will be responsible for building the medical affairs strategy for the clinical stage asset, LOXO-305, a BTK Inhibitor. Provide medical/clinical expertise related to internal (commercial, regulatory affairs, R&D) and external (healthcare professionals, professional societies, advocacy groups, etc.) partners surrounding LOXO-305 program. Additionally, provide strategic and operational direction as well as guidance on opportunities/challenges that may be forecasted.
The physical demands of this job are consistent with light office duties. Travel required up to 50% (US and International).
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office with up to 50% travel as needed (US and International).
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Associate Director, Drug Discovery
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
Loxo Oncology’s Drug Discovery team in Boulder, Colorado has an immediate opening for Medicinal Chemistry Research Associate/ Associate Medicinal Chemists. The Loxo Drug Discovery team’s mission is to invent life-changing targeted therapies for cancer patient populations that are poorly treated by existing therapies. To that end, we have built a multi-disciplinary team of dedicated drug discovery scientists who are passionate about driving the science forward to create highly selective drugs for known oncogenic drivers. We are currently looking for medicinal chemists with a proven track record of success in synthetic organic chemistry. The ideal candidate will be passionate about using synthetic chemistry and data analysis skills to solve medicinal chemistry challenges and will excel at working closely with scientists across disciplines. The position requires excellent people skills, a positive can-do attitude, and the ability to thrive in a highly interactive, fast-paced, team environment.
The physical demands of this position are consistent with working in a laboratory/ bench environment. Some light lifting and maneuvering may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is based in a laboratory/ bench environment.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, National Diagnostics Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
As a member of this regionally-based commercial team, the Precision Medicine Consultant (PMC) will serve as the diagnostics subject matter expert with responsibility for targeted outreach to pathologists, lab directors, oncologists and other account stakeholders to educate on oncology biomarker/genomic testing.
The PMC will leverage account-specific business plans to define opportunities and establish solutions to drive quality testing uptake which will aid in identification of oncology patients who may benefit from targeted therapies.
The PMC may also provide account personnel with appropriate (non-patient specific) education and support around coverage, coding and claims administration of diagnostic testing. Customer segments will focus on academic centers and hospital owned/affiliated community oncology accounts, potentially including regional and specialty reference labs.
Successful PMCs will work compliantly within the Loxo Oncology commercial organization and in close collaboration with Loxo Oncology and Lilly Oncology Sales, Managed Markets, Marketing, Medical Affairs, MSLs, Account Managers, Clinical Support Specialists. Ideal candidates will possess a depth of knowledge in the oncology market and functional knowledge in the clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing. Advanced knowledge of molecular diagnostic testing modalities including next generation sequencing is strongly desired.
Please note this role will require 70-80% US travel, primarily within assigned region but also nationally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, National Diagnostics Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
As a member of this regionally-based commercial team, the Precision Medicine Consultant (PMC) will serve as the diagnostics subject matter expert with responsibility for targeted outreach to pathologists, lab directors, oncologists and other account stakeholders to educate on oncology biomarker/genomic testing.
The PMC will leverage account-specific business plans to define opportunities and establish solutions to drive quality testing uptake which will aid in identification of oncology patients who may benefit from targeted therapies.
The PMC may also provide account personnel with appropriate (non-patient specific) education and support around coverage, coding and claims administration of diagnostic testing. Customer segments will focus on academic centers and hospital owned/affiliated community oncology accounts, potentially including regional and specialty reference labs.
Successful PMCs will work compliantly within the Loxo Oncology commercial organization and in close collaboration with Loxo Oncology and Lilly Oncology Sales, Managed Markets, Marketing, Medical Affairs, MSLs, Account Managers, Clinical Support Specialists. Ideal candidates will possess a depth of knowledge in the oncology market and functional knowledge in the clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing. Advanced knowledge of molecular diagnostic testing modalities including next generation sequencing is strongly desired.
Please note this role will require 70-80% US travel, primarily within assigned region but also nationally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, National Diagnostics Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
As a member of this regionally-based commercial team, the Precision Medicine Consultant (PMC) will serve as the diagnostics subject matter expert with responsibility for targeted outreach to pathologists, lab directors, oncologists and other account stakeholders to educate on oncology biomarker/genomic testing.
The PMC will leverage account-specific business plans to define opportunities and establish solutions to drive quality testing uptake which will aid in identification of oncology patients who may benefit from targeted therapies.
The PMC may also provide account personnel with appropriate (non-patient specific) education and support around coverage, coding and claims administration of diagnostic testing. Customer segments will focus on academic centers and hospital owned/affiliated community oncology accounts, potentially including regional and specialty reference labs.
Successful PMCs will work compliantly within the Loxo Oncology commercial organization and in close collaboration with Loxo Oncology and Lilly Oncology Sales, Managed Markets, Marketing, Medical Affairs, MSLs, Account Managers, Clinical Support Specialists. Ideal candidates will possess a depth of knowledge in the oncology market and functional knowledge in the clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing. Advanced knowledge of molecular diagnostic testing modalities including next generation sequencing is strongly desired.
Please note this role will require 70-80% US travel, primarily within assigned region but also nationally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, National Diagnostics Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
As a member of this regionally-based commercial team, the Precision Medicine Consultant (PMC) will serve as the diagnostics subject matter expert with responsibility for targeted outreach to pathologists, lab directors, oncologists and other account stakeholders to educate on oncology biomarker/genomic testing.
The PMC will leverage account-specific business plans to define opportunities and establish solutions to drive quality testing uptake which will aid in identification of oncology patients who may benefit from targeted therapies.
The PMC may also provide account personnel with appropriate (non-patient specific) education and support around coverage, coding and claims administration of diagnostic testing. Customer segments will focus on academic centers and hospital owned/affiliated community oncology accounts, potentially including regional and specialty reference labs.
Successful PMCs will work compliantly within the Loxo Oncology commercial organization and in close collaboration with Loxo Oncology and Lilly Oncology Sales, Managed Markets, Marketing, Medical Affairs, MSLs, Account Managers, Clinical Support Specialists. Ideal candidates will possess a depth of knowledge in the oncology market and functional knowledge in the clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing. Advanced knowledge of molecular diagnostic testing modalities including next generation sequencing is strongly desired.
Please note this role will require 70-80% US travel, primarily within assigned region but also nationally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, National Diagnostics Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
As a member of this regionally-based commercial team, the Precision Medicine Consultant (PMC) will serve as the diagnostics subject matter expert with responsibility for targeted outreach to pathologists, lab directors, oncologists and other account stakeholders to educate on oncology biomarker/genomic testing.
The PMC will leverage account-specific business plans to define opportunities and establish solutions to drive quality testing uptake which will aid in identification of oncology patients who may benefit from targeted therapies.
The PMC may also provide account personnel with appropriate (non-patient specific) education and support around coverage, coding and claims administration of diagnostic testing. Customer segments will focus on academic centers and hospital owned/affiliated community oncology accounts, potentially including regional and specialty reference labs.
Successful PMCs will work compliantly within the Loxo Oncology commercial organization and in close collaboration with Loxo Oncology and Lilly Oncology Sales, Managed Markets, Marketing, Medical Affairs, MSLs, Account Managers, Clinical Support Specialists. Ideal candidates will possess a depth of knowledge in the oncology market and functional knowledge in the clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing. Advanced knowledge of molecular diagnostic testing modalities including next generation sequencing is strongly desired.
Please note this role will require 70-80% US travel, primarily within assigned region but also nationally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Senior Director, National Diagnostics Lead
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
As a member of this regionally-based commercial team, the Precision Medicine Consultant (PMC) will serve as the diagnostics subject matter expert with responsibility for targeted outreach to pathologists, lab directors, oncologists and other account stakeholders to educate on oncology biomarker/genomic testing.
The PMC will leverage account-specific business plans to define opportunities and establish solutions to drive quality testing uptake which will aid in identification of oncology patients who may benefit from targeted therapies.
The PMC may also provide account personnel with appropriate (non-patient specific) education and support around coverage, coding and claims administration of diagnostic testing. Customer segments will focus on academic centers and hospital owned/affiliated community oncology accounts, potentially including regional and specialty reference labs.
Successful PMCs will work compliantly within the Loxo Oncology commercial organization and in close collaboration with Loxo Oncology and Lilly Oncology Sales, Managed Markets, Marketing, Medical Affairs, MSLs, Account Managers, Clinical Support Specialists. Ideal candidates will possess a depth of knowledge in the oncology market and functional knowledge in the clinical/scientific aspects of cancer diagnosis and biomarker/genomic testing. Advanced knowledge of molecular diagnostic testing modalities including next generation sequencing is strongly desired.
Please note this role will require 70-80% US travel, primarily within assigned region but also nationally as required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is remote based, with significant travel on a regional basis to various sites.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Senior Molecular Cell Biologist will be part of the Loxo Oncology’s Drug Discovery group in Boulder, Colorado. The Drug Discovery group is responsible for identifying molecular targets for life-changing oncology drugs, creating and evaluating novel drug candidates with a focus on small molecule drugs, and providing forward-thinking approaches to advance our clinical portfolio. The Senior/Principal Cell Biologist will be responsible for creating and evaluating cellular assays, execution strategies to quantitatively determine the potency and selectivity of small molecule compounds and interrogate signaling pathways. The Senior Cell Biologist will have a strong understanding of signal transduction pathways and experience in designing experiments to evaluate molecular interactions and pathways. The Senior/Principal Cell Biologist will be part of the team designing, managing and evaluating in vivo pre-clinical studies. This is a hands-on position for an experienced lab scientist who enjoys working in the lab. This scientist must have excellent people skills and be able to work with a positive, “can-do” attitude in a dynamic, fast-paced, team environment focused on high quality science to deliver innovative cancer drugs.
Required:
Ideal candidate will also have:
The physical demands of this position are consistent with working in a laboratory/bench environment. Some light lifting, and maneuvering may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is based in a laboratory/bench environment.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Associate Director, Clinical Science
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
This position offers the opportunity to participate in the entire spectrum of the drug development process. We design our drugs “from the ground up”, starting with the selection of a target we hypothesize is critical for cancer survival and producing a highly potent and specific inhibitor of that single target. As the Senior Clinical Scientist, you will have the opportunity to not only move this drug “from the bench to the bedside”, from initial planning of the first-in-human clinical trial to the pivotal studies necessary to prove its clinical efficacy and gain regulatory approval but also lead a team of Clinical Scientists. You will participate directly in improving the lives of people fighting their cancers.
In your role, you will team with the medical monitor and other team members to design, implement execute and analyze results for Phase 1, 2 and 3 clinical trials for ultimate culmination in clinical study reports and NDA/MAA submissions. Excellent communication skills are important, as you will interact with a variety of collaborators, including colleagues, outside consultants, clinical research sites, and key opinion leaders.
We are a small company, but we are highly focused on clinical and regulatory execution. As a key member of our team, you will have the opportunity to work and learn in a fast-paced, team-oriented and exciting work environment that will literally change the lives of cancer patients for the better.
The Senior Clinical Scientist will help translate preclinical discoveries into developing the next generation of cancer therapies and will be responsible for the design, implementation, and monitoring of clinical development programs. These programs include early proof of concept through registration in a variety of targets and may involve collaborations with corporate development partners. Responsibilities encompass strategic planning to ensure optimized clinical development plans for assigned projects. This person must be interested in working in a fast-paced, team-oriented environment and be adaptable to rapidly changing priorities.
The physical demands of this job are consistent with light office duties.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is in an office.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Associate Director, Medicinal Chemistry
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
Loxo Oncology’s Drug Discovery team has an immediate opening for an experienced medicinal chemist. The Loxo Drug Discovery team’s mission is to develop life-changing targeted therapies for cancer patient populations that are poorly treated by existing therapies. To that end, we have built a multi-disciplinary team of dedicated drug discovery scientists who are passionate about driving the science forward to create highly selective drugs for known oncogenic drivers. We are currently looking for accomplished medicinal chemists with a proven track records of success in small molecule drug discovery. The ideal candidate will be passionate about leading from the bench to solve medicinal chemistry challenges and will excel at working closely with scientists across disciplines. The position requires excellent people skills, a positive can-do attitude, and the ability to thrive in a highly interactive, fast-paced, team environment.
The physical demands of this position are consistent with working in a laboratory/ bench environment. Some light lifting and maneuvering may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is based in a laboratory/ bench environment.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Director, Statistical Programming
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
The Statistical Programmer is responsible for providing Statistical Programming activities across in support of one or more clinical stage programs. Responsibilities will include: support of workflow in generation of study-specific and ad-hoc clinical data listings, summary tables and figures; performing data analysis, statistical analysis, generate safety and efficacy tables, listings and graphs using Base SAS, SAS Macros, SAS/STAT, SAS/Graph, SAS/SQL and SAS/ODS.
This position will travel occasionally based upon the demands of the business imperatives.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is based in a typical office setting.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
TBD
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
This position offers the opportunity to be part of Loxo’s discovery teams focused on creating novel, highly specific and selective drugs for genetically identified targets. The Structural Biologist will offer structural and mechanistic insights to a multi-disciplinary discovery team by delivering high quality protein, protein: small molecule complex crystals, and protein-ligand crystal structures.
There are no physical/travel demands for this job.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
This position’s work environment is based equally in a wet lab and office environment.
The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform each roles and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Outstanding Team Member
Stamford, CT, South San Francisco, CA, or Boulder, CO (or another location to be determined)
Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by that goal. We pursue this goal with a tenacity, focus and commitment to excellence that defines who we are and how we work.
We seek dedicated, passionate, hardworking intelligent, thoughtful and authentic individuals who thrive within a collaborative and fast-paced environment and will bring their experiences, unique perspectives and problem-solving skills to the team. In return, we cultivate an environment that rewards and recognizes hard work and provides opportunities for learning and growth as part of a team making a meaningful difference in the field of medicine and for individual patients.
If you share our passion, please let us know how you could contribute to our team. We don't want to pass up an opportunity for the right candidate to join us just because you found us before we found you.
Submit your resume and your "Who", "What" and "Why" (see below) to careers@loxooncology.com.
Your "Who", "What" and "Why":
Loxo is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.