Career Opportunities

Career Opportunities

Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by our goal of improving the lives of people living with cancer. We pursue this goal with a tenacity, focus, and commitment to excellence that defines who we are and how we work.

We seek dedicated, passionate, hardworking, intelligent, thoughtful, and authentic individuals who thrive within a collaborative and fast-paced environment and will bring their experiences, unique perspectives and problem-solving skills to the team. In return, we cultivate an environment that rewards and recognizes hard work and provides opportunities for learning and growth as part of a team making a meaningful difference in the lives of patients.

Scientist, BioImaging, Discovery Technologies

Location: New York, NY

Reports To:

Imaging Leader, Discovery Technologies

Position Summary

Loxo Oncology at Lilly conducts discovery research, clinical development and regulatory affairs for oncology, with the goal of creating a pipeline of therapies that have the potential to make a meaningful difference for patients. Loxo Oncology at Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. The unit has team members in Boulder, CO, Indianapolis, IN, New York City, South San Francisco, Stamford, CT, and Madrid, Spain.

As a Scientist in the Discovery Technologies, Imaging group, you will be joining a large and dynamic group focused on executing experiments on the cutting edge of pharmaceutical sciences. You will design and conduct experiments needed to support the various research programs for identified targets. You will be expected to demonstrate expertise with high-quality imaging needed for biological sciences (e.g., confocal, live cell imaging, 3D assays) and well versed in all aspects of image analysis. You will be responsible for maintenance of the imaging facilities and to liaise with instrument manufacturers to ensure Loxo’s imaging facilities remain state-of-the-art. You will also be encouraged to develop your own ideas and contribute these to the broader group. You are expected to be a dynamic and motivated scientist who can drive their own experiments and research activities, while collaborating extensively with the rest of the organization to execute on various research programs.

Roles and Responsibilities of the Position*

Scientific roles and responsibilities

  • Design and execute studies using confocal microscopy and live cell imaging instruments
  • Assay development and cell line engineering to generate fluorescent fusions and novel signaling reporter assays
  • Image cell-cell interactions (i.e., CD3 redirection), cells expressing proteins of interest (i.e., cytokines, tumor associated antigens, organelles etc.), subcellular localization, trafficking, plasma membrane dynamics
  • Image analysis and algorithm development, data management
  • Maintain imaging facility instruments and become point of contact for any and all imaging needs for entire R&D organization
  • Interrogate experimental conduct of third parties/vendors
  • Facilitate experiments with in vivo pharmacology group

Additional responsibilities:

  • Communicate results at project team meetings, be involved in the coordination and preparation of presentations
  • Responsible for writing reports (internal and/or regulatory)
  • Discuss results with technical as well as non-technical personnel
  • Work in cross functional environments via extensive collaboration with other parts of the organization
  • Opportunity to directly manage junior scientists in the future
Required Qualifications and Background
  • BSc. in biological sciences with 5+ years of experience or MSc or PhD in biological sciences with 2-3 years of experience
Additional Preferred Qualifications
  • PhD preferred
  • Extensive expertise in confocal microscopy and live cell imaging, assay development, high content imaging, signaling reporter assays, TIRF and image analysis
  • Experience with super resolution microscopy highly desirable
  • Experience in drug discovery an asset
  • Experience in automation and high throughput screening an asset
  • Deep expertise in translational biology concepts, history of working with organoids and 3D assays, as well as in vivo models (e.g., mice models) considered an asset
  • Expertise in cancer disease states (indications, mutational status, tumor cell drivers)
  • Demonstrated experience in working collaboratively across various scientific disciplines to meet end goals of business
  • Demonstrated ability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines
  • Excellent written, verbal communication and interpersonal skills
Physical Demands / Travel

Travel for this role will be <5%. The physical demands of this job are consistent with a laboratory/bench setting. 

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

You will be working in our state-of-the-art laboratories in our NYC facility.

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each role and responsibility satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Loxo Oncology, Inc. is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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