Career Opportunities

Career Opportunities


Patients are at the heart of everything we do at Loxo Oncology, and we continue to be motivated by our goal of improving the lives of people living with cancer. We pursue this goal with a tenacity, focus, and commitment to excellence that defines who we are and how we work.

We seek dedicated, passionate, hardworking, intelligent, thoughtful, and authentic individuals who thrive within a collaborative and fast-paced environment and will bring their experiences, unique perspectives and problem-solving skills to the team. In return, we cultivate an environment that rewards and recognizes hard work and provides opportunities for learning and growth as part of a team making a meaningful difference in the lives of patients.

Scientist, Cell Biology, Bioassay Screening

Location: New York, NY

Reports To:

Director, Mechanistic Biology

Position Summary

Loxo Oncology at Lilly conducts discovery research, clinical development and regulatory affairs for oncology, with the goal of creating a pipeline of therapies that have the potential to make a meaningful difference for patients. Loxo Oncology at Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. The unit has team members in Boulder, CO, Indianapolis, IN, New York City, South San Francisco, Stamford, CT, and Madrid, Spain.

The Scientist, Cell Biology, Bioassay Screening will be responsible for identifying, developing, and performing robust, reproducible cell assays to support drug discovery and development in a team environment. The Scientist, Cell Biology, Bioassay Screening will provide hands-on compound testing to support the small molecule drug discovery oncology pipeline. The scientist fulfilling this position will be responsible for characterizing the effects of small molecule compounds on specific protein targets in cells using multiple cell-based assay formats, examples include HTRF, ELISA, In-Cell Western, Flow cytometry- based cell cycle analysis, Mesoscale, and proliferation.  A strong background in experimental curve-fitting, statistics, and assay optimization and execution is required.

Roles and Responsibilities of the Position*

  • Cell Culture Expertise
  • Develop robust cell-based assays
  • Design, execute, and trouble-shoot experiments
  • Experience in the following assay formats: HTRF, ELISA, In-Cell Western, Flow cytometry, Mesoscale, and Chemiluminescence 
  • CRISPR and Cloning experience is a plus
  • Perform comprehensive data analysis
  • Communicate experimental findings to team members
  • Operate, implement and troubleshoot laboratory automation
  • Actively engaged in advancing drug discovery programs 
  • This is a “hands-on” laboratory, based position

Required Qualifications and Background

  • BS/MS in biology, biochemistry or related fields
  • 3+ years of experience culturing cells and performing cell assays
  • A scientific foundation in the understanding and implementation of a wide range of cell-based screening assays and readouts
  • Excellent oral and written communication skills including experimental documentation
  • Works well with team members daily across functional areas
  • Continual learner who works independently and possesses a can-do attitude
  • Ability to multi-task and shift priorities rapidly to meet tight deadlines
  • Highly organized with exceptional attention to detail
  • Proficient in Microsoft Office suite and applications

Additional Preferred Qualifications

  • Experience in biotech or pharma environment
  • A scientific foundation in the understanding and implementation of a wide range of cell-based screening assays and readouts
  • Excellent oral and written communication skills including experimental documentation
  • Works well with team members daily across functional areas
  • Continual learner who works independently and possesses a can-do attitude
  • Ability to multi-task and shift priorities rapidly to meet tight deadlines
  • Highly organized with exceptional attention to detail

Physical Demands / Travel

The physical demands of this job are consistent with a lab.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment

This position’s work environment is in a lab.  

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform each role and responsibility satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Loxo Oncology, Inc. is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.